Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.71 |
| ▸ | PPARA | Q07869 | 18/20 | 0.71 |
| ▸ | PPARD | Q03181 | 4/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893576 | 0.89 | PPARG (0.73) | PPARGPPARAPPARD | |
| SCHEMBL4898812 | 0.89 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL14111358 | 0.87 | PPARG (0.74) | PPARGPPARAPPARD | |
| SCHEMBL4897062 | 0.85 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL4895436 | 0.84 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL4891116 | 0.83 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL20235377 | 0.83 | PPARG (0.87) | PPARGPPARAPPARD | |
| SCHEMBL4891304 | 0.82 | PPARG (0.87) | PPARGPPARAPPARD | |
| SCHEMBL4896745 | 0.82 | PPARG (0.74) | PPARGPPARAPPARD | |
| SCHEMBL4896190 | 0.82 | PPARG (0.66) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | disclosed |