Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042942 | 0.80 | HPGD (0.48) | MEN1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL9351057 | 0.78 | MEN1 (0.72) | MEN1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL1772778 | 0.76 | HPGD (0.78) | MEN1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL21316776 | 0.76 | NQO1 (0.56) | MEN1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL15346150 | 0.74 | MEN1 (0.50) | MEN1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL8947940 | 0.74 | USP2 (0.58) | MEN1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL5246891 | 0.73 | AKR1C3 (0.70) | MEN1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL722615 | 0.73 | HPGD (1.00) | MEN1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL17088304 | 0.73 | USP2 (0.62) | MEN1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL17088308 | 0.73 | MEN1 (0.49) | MEN1KMT2AKDM4EHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648901-A1 | SUBSTITUTED FUROCHROMENE COMPOUNDS OF ANTIINFLAMMATORY ACTION | PLIVA-ISTRAZIVACKI INSTITUT d.o.o. (HR) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005010006-A1 | SUBSTITUTED FUROCHROMENE COMPOUNDS OF ANTIINFLAMMATORY ACTION | PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2005-02-03 | — | — | WO | disclosed |