Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 19/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5731216 | 1.00 | HMGCR (0.60) | HMGCR | |
| SCHEMBL6495655 | 0.97 | HMGCR (0.63) | HMGCR | |
| SCHEMBL5731011 | 0.97 | HMGCR (0.63) | HMGCR | |
| SCHEMBL5731526 | 0.93 | HMGCR (0.68) | HMGCR | |
| SCHEMBL5731522 | 0.93 | HMGCR (0.68) | HMGCR | |
| SCHEMBL5732479 | 0.91 | HMGCR (0.70) | HMGCR | |
| SCHEMBL5732482 | 0.91 | HMGCR (0.70) | HMGCR | |
| SCHEMBL5732355 | 0.87 | HMGCR (0.67) | HMGCR | |
| SCHEMBL6501904 | 0.87 | HMGCR (0.72) | HMGCR | |
| SCHEMBL6504724 | 0.87 | HMGCR (0.72) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1691803-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | Warner-Lambert Company LLC (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056004-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-23 | — | — | WO | disclosed |