Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 16/20 | 0.39 |
| ▸ | APOB | P04114 | 1/20 | 0.39 |
| ▸ | KLRK1 | P26718 | 3/20 | 0.39 |
| ▸ | MICA | Q29983 | 3/20 | 0.39 |
| ▸ | RAET1L | Q5VY80 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732554 | 0.93 | MTTP (0.39) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL5732561 | 0.93 | MTTP (0.39) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL5065167 | 0.85 | MTTP (0.45) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL5732881 | 0.85 | MTTP (0.43) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL5065180 | 0.84 | MTTP (0.44) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL14031477 | 0.83 | MTTP (0.38) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL5733141 | 0.82 | MTTP (0.37) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL5733451 | 0.82 | MTTP (0.41) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL14031577 | 0.82 | MTTP (0.41) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL5065847 | 0.81 | MTTP (0.41) | MTTPAPOBKLRK1MICARAET1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669345-A1 | ESTER DERIVATIVE AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2006-06-14 | — | — | EP | claimed |
| US-7432392-B2 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2008-10-07 | — | — | US | disclosed |
| US-7432392-B2 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2008-10-07 | — | — | US | disclosed |
| EP-1669345-A1 | ESTER DERIVATIVE AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2006-06-14 | — | — | EP | disclosed |