Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 19/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732553 | 1.00 | HMGCR (0.94) | HMGCR | |
| SCHEMBL5732746 | 0.97 | HMGCR (0.96) | HMGCR | |
| SCHEMBL5732499 | 0.97 | HMGCR (0.96) | HMGCR | |
| SCHEMBL5731912 | 0.97 | HMGCR (1.00) | HMGCR | |
| SCHEMBL5731751 | 0.96 | HMGCR (0.95) | HMGCR | |
| SCHEMBL5731102 | 0.96 | HMGCR (0.88) | HMGCR | |
| SCHEMBL5731405 | 0.96 | HMGCR (0.88) | HMGCR | |
| SCHEMBL5732765 | 0.96 | HMGCR (0.95) | HMGCR | |
| SCHEMBL5731926 | 0.96 | HMGCR (0.98) | HMGCR | |
| SCHEMBL5730882 | 0.96 | HMGCR (0.98) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1691803-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | Warner-Lambert Company LLC (US) | 2006-08-23 | — | — | EP | claimed |
| WO-2005056004-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-23 | — | — | WO | claimed |
| EP-1691803-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | Warner-Lambert Company LLC (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056004-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-23 | — | — | WO | disclosed |