Ethylbenzene

Ethylbenzene

SCHEMBL5732883

CCc1ccccc1.NOCc1ccccc1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 14/20 0.77
AGXT P21549 11/20 0.74
TP53 P04637 1/20 0.64
TSHR P16473 1/20 0.48
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxyamine SCHEMBL7883410 0.88 IDO1 (0.81) IDO1AGXTTSHR
SCHEMBL1714959 0.88 AGXT (0.65) IDO1AGXTCYP3A4
SCHEMBL7948 0.88
SCHEMBL20469087 0.88 IDO1 (1.00) IDO1AGXTTSHRCYP3A4
Ethylbenzene SCHEMBL6896212 0.86 TP53 (0.70) IDO1AGXTTP53TSHR
SCHEMBL8863651 0.85 IDO1 (0.94) IDO1AGXTTSHRCYP3A4
SCHEMBL8021019 0.85 IDO1 (0.94) IDO1AGXTTSHRCYP3A4
Hydrochloric Acid SCHEMBL128937 0.85 AGXT (1.00) IDO1AGXTTSHRCYP3A4
Bromide SCHEMBL8996427 0.85 IDO1 (0.94) IDO1AGXTTSHRCYP3A4
Hydrochloric Acid SCHEMBL27822689 0.85 AGXT (1.00) IDO1AGXTTSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0901996-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES MITSUI CHEMICALS INC (JP) 2006-02-01 EP disclosed
US-6222072-B1 RACTING IMINE WITH HYDRIDE REAGENT IN PRESENCE OF OPTICALLY ACTIVE METAL COMPOUND, WHEREIN HYDRIDE REAGENT IS A METAL HYDRIDE, REAGENT THAT UNDERGOES METAL EXCHANGE, METAL TRIALKOXY HYDRIDE COMPLEX OR METAL(TRICARBOXYLIC ACID)HYDRIDE MITSUI CHEMICALS INC. (JP) 2001-04-24 US disclosed
EP-0901996-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES Mitsui Chemicals, Inc. (JP) 1999-03-17 EP disclosed