SCHEMBL5733191

SCHEMBL5733191

OCCCC(O)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.43
PKM P14618 1/20 0.41
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20449529 0.92 CETP (0.42) CETPPKMLMNAHTTKMT2A
SCHEMBL14152436 0.82
SCHEMBL2988228 0.82
SCHEMBL2988235 0.82
SCHEMBL23176128 0.80 CETP (0.46) CETPPKMLMNAHTTKMT2A
SCHEMBL6900736 0.80 CETP (0.46) CETPPKMLMNAHTTKMT2A
SCHEMBL6230212 0.78 CETP (0.56) CETPPKMLMNAHTTKMT2A
SCHEMBL6252448 0.76 CETP (0.42) CETPPKM
SCHEMBL14560675 0.76 CETP (0.42) CETPPKM
SCHEMBL10716317 0.76 CETP (0.42) CETPPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0901996-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES MITSUI CHEMICALS INC (JP) 2006-02-01 EP disclosed
EP-0667332-A1 PROCESS FOR PRODUCING FLUORINATED DICARBONYL COMPOUND DAIKIN INDUSTRIES, LIMITED (JP) 1995-08-16 EP disclosed
US-4008139-A Fluorinated compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-02-15 US disclosed