Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.51 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5729673 | 0.99 | F10 (0.51) | F10F2PLATKLKB1 | |
| SCHEMBL5731177 | 0.91 | F10 (0.49) | F10F2PLATKLKB1 | |
| SCHEMBL5730431 | 0.89 | F10 (0.55) | F10 | |
| Hydrochloric Acid SCHEMBL5729006 | 0.89 | F10 (0.54) | F10 | |
| Hydrochloric Acid SCHEMBL5730562 | 0.86 | F10 (0.56) | F10F2PLATKLKB1 | |
| SCHEMBL5729592 | 0.81 | F10 (0.57) | F10 | |
| SCHEMBL5729156 | 0.81 | F10 (0.49) | F10F2PLATKLKB1 | |
| Hydrochloric Acid SCHEMBL5728808 | 0.80 | F10 (0.56) | F10 | |
| SCHEMBL5729785 | 0.79 | F10 (0.50) | F10F2PLATKLKB1 | |
| SCHEMBL5729315 | 0.79 | F10 (0.53) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |