Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 14/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198847 | 0.91 | F10 (0.55) | ATMF10SMN1; SMN2GAALMNA | |
| SCHEMBL6198681 | 0.91 | F10 (0.55) | ATMF10SMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL6197321 | 0.91 | F10 (0.55) | ATMF10SMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL6196916 | 0.91 | F10 (0.54) | ATMF10SMN1; SMN2GAALMNA | |
| SCHEMBL5193868 | 0.89 | ATM (0.71) | ATMF10SMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL6195419 | 0.88 | ATM (0.69) | ATMF10SMN1; SMN2GAALMNA | |
| SCHEMBL6193507 | 0.86 | F10 (0.50) | ATMF10SMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL6198357 | 0.85 | F10 (0.49) | ATMF10SMN1; SMN2GAALMNA | |
| SCHEMBL6577783 | 0.84 | SMN1; SMN2 (0.59) | ATMF10SMN1; SMN2GAALMNA | |
| Hydrochloric Acid SCHEMBL6200516 | 0.84 | F10 (0.58) | ATMF10SMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |