Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438341 | 0.87 | NPC1 (0.89) | NPC1RAB9AKMT2ANR1H4GSK3B | |
| SCHEMBL4883318 | 0.81 | NPC1 (1.00) | NPC1RAB9AKDM4EKMT2ANR1H4 | |
| SCHEMBL12171414 | 0.80 | NPC1 (0.96) | NPC1RAB9AKDM4EKMT2ANR1H4 | |
| SCHEMBL12171885 | 0.80 | NPC1 (0.77) | NPC1RAB9AKMT2ANR1H4GSK3B | |
| SCHEMBL12171934 | 0.79 | NPC1 (0.74) | NPC1RAB9AKDM4EKMT2ANR1H4 | |
| SCHEMBL12171408 | 0.79 | NPC1 (0.74) | NPC1RAB9AKDM4EDGAT1KMT2A | |
| SCHEMBL12798171 | 0.79 | NPC1 (0.74) | NPC1RAB9AKMT2ANR1H4GSK3B | |
| SCHEMBL12170932 | 0.79 | NPC1 (0.74) | NPC1RAB9AKMT2ANR1H4MYC | |
| SCHEMBL70030 | 0.79 | NPC1 (0.69) | NPC1RAB9AKMT2ANR1H4GSK3B | |
| SCHEMBL12171897 | 0.79 | NPC1 (0.74) | NPC1RAB9ANOTUMKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980222-A | 2-amido-5-substituted-1,3,4-oxadiazole as well as preparation method and application thereof | UNIV SHAANXI SCIENCE & TECH | 2014-08-13 | — | — | CN | disclosed |
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |