Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | RORC | P51449 | 6/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP7 | P09237 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733667 | 1.00 | F10 (0.41) | F10RORCMMP1MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL7660180 | 0.99 | F10 (0.40) | F10RORCMMP1MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL7660172 | 0.99 | F10 (0.40) | F10RORCMMP1MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL5734521 | 0.88 | F10 (0.41) | F10MMP1MMP3MMP7MMP9 | |
| Hydrochloric Acid SCHEMBL5734525 | 0.88 | F10 (0.41) | F10MMP1MMP3MMP7MMP9 | |
| Hydrochloric Acid SCHEMBL5733749 | 0.85 | F10 (0.44) | F10MMP1MMP3MMP7MMP9 | |
| Hydrochloric Acid SCHEMBL5733752 | 0.85 | F10 (0.44) | F10MMP1MMP3MMP7MMP9 | |
| SCHEMBL5735437 | 0.85 | F10 (0.41) | F10RORCKMT2ASMN1; SMN2 | |
| SCHEMBL5735439 | 0.85 | F10 (0.41) | F10RORCKMT2ASMN1; SMN2 | |
| SCHEMBL5735808 | 0.83 | F10 (0.57) | F10CNR1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |