Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 17/20 | 0.77 |
| ▸ | TACR3 | P29371 | 18/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5733578 | 0.92 | TACR3 (0.74) | TACR2TACR3OPRM1KCNH2TRPV4 | |
| SCHEMBL5734676 | 0.92 | TACR3 (0.75) | TACR2TACR3OPRM1KCNH2TRPV4 | |
| SCHEMBL5734222 | 0.89 | TACR2 (0.66) | TACR2TACR3OPRM1KCNH2TRPV4 | |
| SCHEMBL5733958 | 0.87 | TACR2 (1.00) | TACR2TACR3OPRM1KCNH2TRPV4 | |
| SCHEMBL6199955 | 0.81 | TACR2 (0.66) | TACR2TACR3OPRM1TRPV4 | |
| SCHEMBL5733729 | 0.81 | TACR2 (0.81) | TACR2TACR3OPRM1KCNH2TRPV4 | |
| SCHEMBL3962728 | 0.79 | TACR2 (0.79) | TACR2TACR3OPRM1KCNH2TRPV4 | |
| SCHEMBL6201403 | 0.79 | TACR2 (0.62) | TACR2TACR3OPRM1TRPV4 | |
| Hydrochloric Acid SCHEMBL5732533 | 0.79 | TACR2 (0.77) | TACR2TACR3OPRM1KCNH2TRPV4 | |
| SCHEMBL6203216 | 0.77 | TACR2 (0.63) | TACR2TACR3OPRM1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131294-B1 | QUINOLINE DERIVATIVES AS NK-2 AND NK-3 RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2006-12-20 | — | — | EP | claimed |