Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735292 | 1.00 | F10 (0.50) | F10CNR1PKMNPSR1LMNA | |
| SCHEMBL5735087 | 1.00 | F10 (0.50) | F10CNR1PKMNPSR1LMNA | |
| SCHEMBL5733444 | 0.89 | F10 (0.57) | F10CNR1PKMNPSR1LMNA | |
| SCHEMBL5733446 | 0.89 | F10 (0.57) | F10CNR1PKMNPSR1LMNA | |
| SCHEMBL5735808 | 0.89 | F10 (0.57) | F10CNR1PKMNPSR1LMNA | |
| SCHEMBL5737054 | 0.87 | F10 (0.54) | F10CNR1PKMNPSR1LMNA | |
| SCHEMBL5734088 | 0.83 | F10 (0.59) | F10CNR1PKMNPSR1LMNA | |
| SCHEMBL5734425 | 0.80 | F10 (0.55) | F10CNR1PKMNPSR1GAA | |
| SCHEMBL5734724 | 0.80 | F10 (0.55) | F10CNR1PKMNPSR1LMNA | |
| SCHEMBL5734727 | 0.80 | F10 (0.55) | F10CNR1PKMNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |