Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283931 | 0.94 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL5666699 | 0.94 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL5666356 | 0.91 | BACE1 (0.84) | BACE1CTSD | |
| SCHEMBL5736368 | 0.89 | BACE1 (0.87) | BACE1CTSD | |
| SCHEMBL6041016 | 0.87 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL5672247 | 0.87 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL8281474 | 0.85 | BACE1 (0.73) | BACE1CTSD | |
| SCHEMBL8282550 | 0.85 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL5666264 | 0.85 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL5666486 | 0.85 | BACE1 (0.88) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1734942-A1 | SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005087215-A1 | SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | disclosed |