Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.68 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL211854 | 0.85 | HDAC1 (0.78) | HDAC1AURKBHDAC3HDAC2SCD | |
| SCHEMBL213867 | 0.83 | HDAC1 (0.86) | HDAC1AURKB | |
| SCHEMBL210479 | 0.81 | HDAC1 (0.77) | HDAC1AURKBSCD | |
| SCHEMBL209760 | 0.81 | HDAC1 (0.85) | HDAC1AURKB | |
| SCHEMBL1061039 | 0.81 | HDAC1 (1.00) | HDAC1AURKB | |
| SCHEMBL1064488 | 0.80 | HDAC1 (1.00) | HDAC1SCD | |
| SCHEMBL13390247 | 0.79 | HDAC1 (0.79) | HDAC1AURKB | |
| SCHEMBL214421 | 0.77 | HDAC1 (0.82) | HDAC1HDAC3HDAC2 | |
| SCHEMBL210213 | 0.76 | HDAC1 (0.81) | HDAC1HDAC3HDAC2SCD | |
| SCHEMBL2733826 | 0.76 | HDAC1 (0.79) | HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735319-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005092899-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2005-10-06 | — | — | WO | disclosed |