⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071821 | 0.75 | — | — | |
| SCHEMBL128859 | 0.72 | — | — | |
| SCHEMBL11225684 | 0.72 | — | — | |
| SCHEMBL641605 | 0.72 | — | — | |
| SCHEMBL5586687 | 0.72 | — | — | |
| SCHEMBL25487800 | 0.72 | — | — | |
| SCHEMBL4361943 | 0.69 | — | — | |
| SCHEMBL3166927 | 0.69 | — | — | |
| SCHEMBL13497356 | 0.69 | — | — | |
| SCHEMBL8802931 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916978-A | Oligonucleotides | 哈德森医学研究所 | 2023-04-04 | — | — | CN | disclosed |
| CN-114555095-A | Methods of treating muscular dystrophy using inhibitory oligonucleotides against CD49d | 反义治疗有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-112368001-A | Therapeutic uses and methods | 反义治疗有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-106470688-A | Oligomers and oligomer conjugates | 豪夫迈·罗氏有限公司 | 2017-03-01 | — | — | CN | disclosed |
| EP-2938624-A1 | D-ALANINE ESTER OF SP-NUCLEOSIDE ANALOG | IDENIX Pharmaceuticals, Inc. (US) | 2015-11-04 | — | — | EP | disclosed |
| EP-2920195-A1 | D-ALANINE ESTER OF RP-NUCLEOSIDE ANALOG | IDENIX Pharmaceuticals, Inc. (US) | 2015-09-23 | — | — | EP | disclosed |
| CN-101878193-B | Bicyclic gamma-amino acid derivatives | DAIICHI SANKYO CO LTD | 2014-07-09 | — | — | CN | disclosed |
| WO-2014078427-A1 | D-ALANINE ESTER OF RP-NUCLEOSIDE ANALOG | IDENIX PHARMACEUTICALS, INC. (US) | 2014-05-22 | — | — | WO | disclosed |
| WO-2014078436-A1 | D-ALANINE ESTER OF SP-NUCLEOSIDE ANALOG | IDENIX PHARMACEUTICALS, INC. (US) | 2014-05-22 | — | — | WO | disclosed |
| CN-101878193-A | Bicyclic gamma-amino acid derivatives | DAIICHI SANKYO CO LTD | 2010-11-03 | — | — | CN | disclosed |
| EP-1718603-A2 | NITRIC OXIDE-RELEASING MOLECULES | Noxilizer, Inc. (US) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005081753-A2 | NITRIC OXIDE-RELEASING MOLECULES | NOXILIZER, INC. (US) | 2005-09-09 | — | — | WO | disclosed |
| EP-1084134-A4 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS INC (US) | 2004-05-26 | — | — | EP | disclosed |
| CN-1443190-A | Matrix metalloproteinase inhibitors | LEO PHARM PROD LTD (DK) | 2003-09-17 | — | — | CN | disclosed |
| CN-1087317-C | Block polymer having functional groups at both ends | KAZUNORI KATAOKA (JP) | 2002-07-10 | — | — | CN | disclosed |
| EP-1084134-A1 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS, INC. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062922-A1 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| CN-1202171-A | Pyrido [2,3-d] pyrimidine derivatives and medicinal compositions thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | CN | disclosed |
| CN-1192759-A | Block polymer having functional groups at both ends | KATAOKA KAZUNORI (JP) | 1998-09-09 | — | — | CN | disclosed |
| CN-1102643-A | Substituted derivatives of diaminophthalimide | CIBA GEIGY AG (CH) | 1995-05-17 | — | — | CN | disclosed |