⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732655 | 0.81 | — | — | |
| SCHEMBL2183477 | 0.79 | — | — | |
| SCHEMBL3517557 | 0.70 | — | — | |
| SCHEMBL18724712 | 0.69 | — | — | |
| SCHEMBL5521591 | 0.56 | — | — | |
| SCHEMBL256774 | 0.52 | — | — | |
| Tetramethylene Sulfoxide SCHEMBL27830 | 0.49 | — | — | |
| SCHEMBL10971934 | 0.47 | — | — | |
| SCHEMBL256066 | 0.47 | — | — | |
| SCHEMBL6009379 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468748-A | Nervous system and psychological disorders; antagonize glycine binding site on N-methylaspartic acid receptor complex | NOVO NORDISK A/S (DK) | 1995-11-21 | — | — | US | claimed |
| US-9073954-B2 | 5-substituted benzimidazolium compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-07-07 | — | — | US | disclosed |
| US-9073954-B2 | 5-substituted benzimidazolium compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-07-07 | — | — | US | disclosed |
| CN-103906747-A | Preparation method of cabazitaxel and intermediate thereof | SCINOPHARM TAIWAN LTD | 2014-07-02 | — | — | CN | disclosed |
| US-8722900-B2 | Process for cabazitaxel, and intermediates thereof | SCINOPHARM TAIWAN, LTD. (TW) | 2014-05-13 | — | — | US | disclosed |
| US-20130116444-A1 | PROCESS FOR CABAZITAXEL, AND INTERMEDIATES THEREOF | SCINOPHARM TAIWAN, LTD. (TW) | 2013-05-09 | — | — | US | disclosed |
| EP-1135394-B1 | SPIROCYCLIC THIENOPYRANS AS POTASSIUM CHANNEL ACTIVATORS | CAMBRIDGE BIOCLINICAL LTD (GB) | 2006-03-01 | — | — | EP | disclosed |
| US-6342517-B1 | THIENOPYRAN COMPOUNDS AS HYPOTENSIVE AGENTS | CAMBRIDGE BIOCLINICAL LIMITED (GB) | 2002-01-29 | — | — | US | disclosed |
| EP-1135394-A2 | SPIROCYCLIC THIENOPYRANS AS POTASSIUM CHANNEL ACTIVATORS | CAMBRIDGE BIOCLINICAL LIMITED (GB) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000034287-A2 | SPIROCYCLIC THIENOPYRANS AS POTASSIUM CHANNEL ACTIVATORS | CAMBRIDGE BIOCLINICAL LIMITED (GB) | 2000-06-15 | — | — | WO | disclosed |
| US-4619924-A | BACTERICIDES | PFIZER INC. (US) | 1986-10-28 | — | — | US | disclosed |
| EP-0130025-A1 | 2-Alkylthiopenem derivatives | PFIZER INC. (US) | 1985-01-02 | — | — | EP | disclosed |