Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.43 |
| ▸ | F2 | P00734 | 6/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5734582 | 1.00 | F10 (0.43) | F10F2AKR1C3AKR1C1RAB9A | |
| SCHEMBL5735223 | 0.90 | KMT2A (0.44) | F10F2RAB9AADAM17KMT2A | |
| SCHEMBL5735221 | 0.90 | KMT2A (0.44) | F10F2RAB9AADAM17KMT2A | |
| SCHEMBL5734775 | 0.90 | F10 (0.43) | F10F2RAB9AADAM17CNR1 | |
| SCHEMBL5734768 | 0.90 | F10 (0.43) | F10F2RAB9AADAM17CNR1 | |
| Hydrochloric Acid SCHEMBL5735935 | 0.86 | F10 (0.44) | F10F2AKR1C3AKR1C1RAB9A | |
| Hydrochloric Acid SCHEMBL5735941 | 0.86 | F10 (0.44) | F10F2AKR1C3AKR1C1RAB9A | |
| SCHEMBL5735437 | 0.86 | F10 (0.41) | F10F2RAB9AMEN1KMT2A | |
| SCHEMBL5735439 | 0.86 | F10 (0.41) | F10F2RAB9AMEN1KMT2A | |
| SCHEMBL5733446 | 0.86 | F10 (0.57) | F10MEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |