Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.66 |
| ▸ | CNR1 | P21554 | 7/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736704 | 1.00 | F10 (0.66) | F10CNR1NPSR1LMNAUSP2 | |
| SCHEMBL5736345 | 0.84 | F10 (0.68) | F10CNR1NPSR1LMNAUSP2 | |
| SCHEMBL5735074 | 0.84 | F10 (0.68) | F10CNR1NPSR1LMNAUSP2 | |
| Hydrochloric Acid SCHEMBL5733905 | 0.83 | F10 (0.67) | F10CNR1NPSR1LMNAUSP2 | |
| Hydrochloric Acid SCHEMBL5734077 | 0.83 | F10 (0.67) | F10CNR1NPSR1LMNAUSP2 | |
| Hydrochloric Acid SCHEMBL5733907 | 0.83 | F10 (0.67) | F10CNR1NPSR1LMNAUSP2 | |
| SCHEMBL4942386 | 0.83 | F10 (0.70) | F10CNR1NPSR1LMNAUSP2 | |
| Hydrochloric Acid SCHEMBL5735795 | 0.82 | F10 (0.66) | F10CNR1NPSR1LMNAUSP2 | |
| Hydrochloric Acid SCHEMBL5735799 | 0.82 | F10 (0.66) | F10CNR1NPSR1LMNAUSP2 | |
| Hydrochloric Acid SCHEMBL5735250 | 0.82 | F10 (0.68) | F10CNR1NPSR1LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |