Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 10/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 4/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | GPR142 | Q7Z601 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5737097 | 1.00 | CAPN1 (0.44) | CAPN1FOLH1RENSCN9ACTSB | |
| SCHEMBL5734967 | 1.00 | CAPN1 (0.44) | CAPN1FOLH1RENSCN9ACTSB | |
| SCHEMBL5734974 | 1.00 | CAPN1 (0.44) | CAPN1FOLH1RENSCN9ACTSB | |
| SCHEMBL5737125 | 0.84 | CAPN1 (0.43) | CAPN1RENSCN9ACTSBCTSS | |
| SCHEMBL5735628 | 0.84 | CAPN1 (0.43) | CAPN1RENSCN9ACTSBCTSS | |
| SCHEMBL5737121 | 0.84 | CAPN1 (0.43) | CAPN1RENSCN9ACTSBCTSS | |
| SCHEMBL5735626 | 0.84 | CAPN1 (0.43) | CAPN1RENSCN9ACTSBCTSS | |
| Rovatirelin SCHEMBL20811796 | 0.83 | DPP4 (0.42) | CAPN1REN | |
| Rovatirelin SCHEMBL14280927 | 0.83 | DPP4 (0.42) | CAPN1REN | |
| Rovatirelin SCHEMBL14306794 | 0.83 | DPP4 (0.42) | CAPN1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933379-B1 | NOVEL PEPTIDE DERIVATIVES HAVING THIAZOLYL-ALANINE RESIDUE | SHIONOGI & CO (JP) | 2006-03-22 | — | — | EP | disclosed |
| US-6319902-B1 | TO ACTIVATE THE CENTRAL NERVOUS SYSTEM, SUCH AS, FOR EXAMPLE, SUSTAINED ACETYLCHOLINE RELEASING ACTION, ANTI-RESERPINE ACTION AND LOCOMOTOR INCREMENT | SHIONOGI & CO., LTD. (JP) | 2001-11-20 | — | — | US | disclosed |
| EP-0933379-A1 | NOVEL PEPTIDE DERIVATIVES HAVING THIAZOLYL-ALANINE RESIDUE | SHIONOGI & CO., LTD. (JP) | 1999-08-04 | — | — | EP | disclosed |