Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 4/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.93 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15257780 | 1.00 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL789234 | 1.00 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL789235 | 1.00 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL12958834 | 1.00 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9173411 | 1.00 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6938649 | 1.00 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9173436 | 1.00 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL9166176 | 1.00 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL21710733 | 1.00 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL7070428 | 1.00 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1110554-B1 | MEDICINAL COMPOSITIONS FOR TREATING EYE DISEASES | YAMASA CORP (JP) | 2006-03-08 | — | — | EP | disclosed |
| US-6387889-B1 | REDUCING OCULAR TENSION | YAMASA CORPORATION (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-1110554-A1 | MEDICINAL COMPOSITIONS FOR TREATING EYE DISEASES | YAMASA CORPORATION (JP) | 2001-06-27 | — | — | EP | disclosed |
| US-5459254-A | Reversing the order of the amination and alkynylation steps | YAMASA SHOYU KABUSHIKI KAISHA (JP) | 1995-10-17 | — | — | US | disclosed |
| EP-0429681-B1 | INTERMEDIATE FOR 2-ALKYNYLADENOSINE SYNTHESIS, PRODUCTION OF SAID INTERMEDIATE, PRODUCTION OF 2-ALKYNYLADENOSINE FROM SAID INTERMEDIATE, AND STABLE 2-ALKYNYLADENOSINE DERIVATIVE | YAMASA SHOYU KK (JP) | 1995-09-06 | — | — | EP | disclosed |
| EP-0444196-B1 | AGENT FOR TREATMENT AND PROPHYLAXIS OF ISCHEMIC DISEASE OF HEART OR BRAIN | YAMASA SHOYU KK (JP) | 1994-06-08 | — | — | EP | disclosed |
| US-5283327-A | Synthetic intermediate for 2-alkynyladenosine; storage stability | YAMASA SHOYU KABUSHIKI KAISHA (JP) | 1994-02-01 | — | — | US | disclosed |
| US-5270304-A | Therapeutic 2-alkynyl adenosine agent for ischemic diseases of the heart or brain | YAMASA SHOYU KABUSHIKI KAISHA (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0444196-A1 | AGENT FOR TREATMENT AND PROPHYLAXIS OF ISCHEMIC DISEASE OF HEART OR BRAIN | Yamasa Shoyu Kabushiki Kaisha (JP) | 1991-09-04 | — | — | EP | disclosed |
| EP-0429681-A1 | INTERMEDIATE FOR 2-ALKYNYLADENOSINE SYNTHESIS, PRODUCTION OF SAID INTERMEDIATE, PRODUCTION OF 2-ALKYNYLADENOSINE FROM SAID INTERMEDIATE, AND STABLE 2-ALKYNYLADENOSINE DERIVATIVE | Yamasa Shoyu Kabushiki Kaisha (Yamasa Corporation) (JP) | 1991-06-05 | — | — | EP | disclosed |