Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5739123 | 0.84 | DPP4 (0.49) | DPP4NPC1RAB9APOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL5448900 | 0.81 | DPP4 (0.70) | DPP4 | |
| SCHEMBL5454134 | 0.81 | DPP4 (0.59) | DPP4HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5738848 | 0.81 | DPP4 (0.54) | DPP4HPGDTRPM8NPC1RAB9A | |
| SCHEMBL5740124 | 0.79 | DPP4 (0.44) | DPP4 | |
| SCHEMBL27665023 | 0.77 | DPP4 (0.60) | DPP4 | |
| SCHEMBL5741196 | 0.76 | DPP4 (0.46) | DPP4 | |
| Hydrochloric Acid SCHEMBL27643657 | 0.76 | DPP4 (0.61) | DPP4 | |
| SCHEMBL27664835 | 0.76 | DPP4 (0.51) | DPP4SMN1; SMN2 | |
| SCHEMBL27664836 | 0.74 | DPP4 (0.49) | DPP4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678138-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Takeda Pharmaceutical Company Limited (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042488-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-12 | — | — | WO | disclosed |