Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38658428 | 1.00 | KMT2A (0.39) | KMT2AMEN1CYP2C19CYP2C9HPGD | |
| SCHEMBL19924259 | 1.00 | KMT2A (0.39) | KMT2AMEN1CYP2C19CYP2C9HPGD | |
| SCHEMBL19938125 | 1.00 | KMT2A (0.39) | KMT2AMEN1CYP2C19CYP2C9HPGD | |
| SCHEMBL10072989 | 0.87 | KMT2A (0.45) | KMT2AMEN1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL10047750 | 0.84 | KMT2A (0.43) | KMT2AMEN1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL5738466 | 0.81 | KMT2A (0.38) | KMT2AMEN1CYP2C19CYP2C9HPGD | |
| SCHEMBL24741355 | 0.76 | KMT2A (0.45) | KMT2AMEN1CYP2C19CYP2C9HPGD | |
| SCHEMBL5739207 | 0.76 | KMT2A (0.45) | KMT2AMEN1CYP2C19CYP2C9HPGD | |
| SCHEMBL5739211 | 0.76 | KMT2A (0.45) | KMT2AMEN1CYP2C19CYP2C9HPGD | |
| SCHEMBL38657586 | 0.76 | KMT2A (0.45) | KMT2AMEN1CYP2C19CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219625-B1 | Novel substituted 2-(6-benzyl-5-oxo-3-phenyl-(S3,7S,7AR)- perhydroimidazol (1,5-C) (1,3) thiazol-7YL) compounds | COUNCIL SCIENT IND RES (IN) | 2006-05-17 | — | — | EP | claimed |