Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454715 | 0.85 | DPP4 (0.47) | DPP4DPP9DPP8KDM4A | |
| SCHEMBL4113112 | 0.85 | DPP4 (0.66) | DPP4DPP9DPP8KMT2A | |
| SCHEMBL5451905 | 0.83 | DPP4 (0.48) | DPP4DPP9DPP8KDM4A | |
| SCHEMBL5453608 | 0.83 | DPP4 (0.53) | DPP4DPP9DPP8KMT2A | |
| SCHEMBL5456061 | 0.82 | DPP4 (0.66) | DPP4DPP9DPP8KDM4A | |
| SCHEMBL5739455 | 0.81 | DPP4 (0.46) | DPP4DPP9DPP8KDM4A | |
| SCHEMBL5241529 | 0.81 | DPP4 (0.46) | DPP4DPP9DPP8KDM4A | |
| SCHEMBL5240277 | 0.80 | DPP4 (0.43) | DPP4DPP9DPP8 | |
| SCHEMBL5447087 | 0.79 | DPP4 (0.43) | DPP4DPP9DPP8KMT2A | |
| SCHEMBL5739223 | 0.79 | DPP4 (0.44) | DPP4DPP9DPP8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678138-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Takeda Pharmaceutical Company Limited (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042488-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-12 | — | — | WO | disclosed |