Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738564 | 0.85 | DPP4 (0.46) | DPP4DPP8DPP9 | |
| SCHEMBL5739902 | 0.82 | DPP4 (0.45) | DPP4DPP8DPP9 | |
| SCHEMBL5740996 | 0.81 | DPP4 (0.47) | DPP4DPP8DPP9 | |
| SCHEMBL5739895 | 0.81 | DPP4 (0.44) | DPP4DPP8DPP9 | |
| SCHEMBL5740432 | 0.81 | DPP4 (0.64) | DPP4DPP8DPP9 | |
| SCHEMBL5739263 | 0.81 | DPP4 (0.48) | DPP4DPP8DPP9 | |
| SCHEMBL5741032 | 0.78 | DPP4 (0.51) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5441311 | 0.78 | DPP4 (0.83) | DPP4DPP8DPP9 | |
| SCHEMBL5740456 | 0.78 | DPP4 (0.45) | DPP4DPP8DPP9 | |
| SCHEMBL5738343 | 0.77 | KDM4E (0.42) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678138-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Takeda Pharmaceutical Company Limited (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042488-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-12 | — | — | WO | disclosed |