⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397914 | 1.00 | — | — | |
| SCHEMBL29189596 | 1.00 | — | — | |
| SCHEMBL31267318 | 1.00 | — | — | |
| SCHEMBL15979225 | 1.00 | — | — | |
| SCHEMBL14367702 | 1.00 | — | — | |
| SCHEMBL18998993 | 1.00 | — | — | |
| SCHEMBL29189595 | 1.00 | — | — | |
| SCHEMBL21497994 | 0.81 | — | — | |
| SCHEMBL18975388 | 0.80 | — | — | |
| SCHEMBL23284422 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12540131-B2 | N-(heteroaryl) quinazolin-2-amine derivatives as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof | MERCK SHARP & DOHME LLC (US) | 2026-02-03 | — | — | US | claimed |
| US-20240398784-A1 | C-LINKED ISOQUINOLINE AMIDES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-12-05 | — | — | US | claimed |
| EP-3288995-B1 | POLYURETHANE-BASED BINDER SYSTEM | HENKEL AG & CO KGAA (DE) | 2024-03-20 | — | — | EP | claimed |
| EP-3910044-B1 | ANTI-FREEZE AGENT | AQUA CONCEPT GES FUER WASSERBEHANDLUNG MBH (DE) | 2024-03-06 | — | — | EP | claimed |
| US-20230023066-A1 | N-(HETEROARYL) QUINAZOLIN-2-AMINE DERIVATIVES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2023-01-26 | — | — | US | claimed |
| EP-3829893-B1 | ERASING TOOL CONTAINING POLYETHERAMINE FOR THERMOCHROMIC INK COMPOSITIONS | SOCIéTé BIC (FR) | 2022-04-27 | — | — | EP | claimed |
| EP-2601201-B1 | PROCESS FOR PREPARATION OF NOVEL 42-0-(HETEROALKOXYALKYL) RAPAMYCIN COMPOUNDS WITH ANTI-PROLIFERATIVE PROPERTIES\ | MERIL LIFE SCIENCES PVT LTD (IN) | 2014-09-24 | — | — | EP | claimed |
| US-20130184305-A1 | PROCESS FOR PREPARATION OF NOVEL 42-O-(HETEROALKOXYALKYL) RAPAMICIN COMPOUNDS WITH ANTI-PROLIFERATIVE PROPERTIES | MERIL LIFE SCIENCES PVT. LTD. (IN) | 2013-07-18 | — | — | US | claimed |
| EP-2601201-A1 | PROCESS FOR PREPARATION OF NOVEL 42-0-(HETEROALKOXYALKYL) RAPAMYCIN COMPOUNDS WITH ANTI-PROLIFERATIVE PROPERTIES\ | Meril Life Sciences Pvt. Ltd. (IN) | 2013-06-12 | — | — | EP | claimed |
| WO-2012017449-A1 | PROCESS FOR PREPARATION OF NOVEL 42-0-(HETEROALKOXYALKYL) RAPAMYCIN COMPOUNDS WITH ANTI-PROLIFERATIVE PROPERTIES\ | MERIL LIFE SCIENCES PVT. LTD (IN) | 2012-02-09 | — | — | WO | claimed |
| EP-4551328-B1 | PROCESS FOR PREPARING DOUBLE METAL CYANIDE CATALYSTS | COVESTRO DEUTSCHLAND AG (DE) | 2026-05-20 | — | — | EP | disclosed |
| EP-4355748-B1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI SA (FR) | 2026-05-13 | — | — | EP | disclosed |
| US-12570640-B2 | 2-aminoquinazolines as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof | MERCK SHARP & DOHME LLC (US) | 2026-03-10 | — | — | US | disclosed |
| US-12540131-B2 | N-(heteroaryl) quinazolin-2-amine derivatives as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof | MERCK SHARP & DOHME LLC (US) | 2026-02-03 | — | — | US | disclosed |
| US-12516039-B2 | N-linked isoquinoline amides as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof | MERCK SHARP & DOHME LLC (US) | 2026-01-06 | — | — | US | disclosed |
| US-20080306051-A1 | HIV Integrase Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2008-12-11 | — | — | US | disclosed |
| US-20080306051-A1 | HIV Integrase Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2008-12-11 | — | — | US | disclosed |
| US-20070161685-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-07-12 | — | — | US | disclosed |
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-14 | — | — | US | disclosed |
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |