Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5739794 | 1.00 | AR (0.67) | ARKMT2AMEN1POLBGLA | |
| SCHEMBL11174171 | 0.84 | AR (0.64) | ARKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL13879545 | 0.81 | AR (0.60) | ARKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL12543889 | 0.81 | AR (0.56) | ARKMT2AMEN1POLBRAB9A | |
| SCHEMBL5740339 | 0.80 | KMT2A (0.72) | ARKMT2AMEN1POLBRAB9A | |
| SCHEMBL13879554 | 0.77 | TSHR (0.61) | ARKMT2APOLBALDH1A1 | |
| SCHEMBL11041126 | 0.77 | AR (0.55) | ARKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL15919496 | 0.77 | AR (0.52) | ARKMT2AMEN1POLBRAB9A | |
| SCHEMBL12542557 | 0.76 | AR (0.56) | ARKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL5740800 | 0.76 | KMT2A (0.66) | ARKMT2AMEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244670-B1 | HYDANTOIN DERIVATIVE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USING SAME | MGI GP INC (US) | 2006-03-08 | — | — | EP | claimed |