Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.78 |
| ▸ | ERBB2 | P04626 | 20/20 | 0.78 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5740882 | 0.95 | EGFR (0.72) | EGFRERBB2 | |
| SCHEMBL5740455 | 0.94 | ERBB2 (0.79) | EGFRERBB2 | |
| SCHEMBL5739155 | 0.90 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL1462065 | 0.88 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL466103 | 0.87 | EGFR (0.84) | EGFRERBB2ERBB4 | |
| SCHEMBL5739460 | 0.86 | ERBB2 (0.72) | EGFRERBB2 | |
| SCHEMBL1730679 | 0.85 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL1730083 | 0.84 | EGFR (0.88) | EGFRERBB2 | |
| SCHEMBL1728685 | 0.84 | EGFR (1.00) | EGFRERBB2ERBB4 | |
| SCHEMBL5738836 | 0.84 | EGFR (0.55) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183033-B1 | PYRROLOTRIAZINE INHIBITORS OF KINASES | BRISTOL MYERS SQUIBB CO (US) | 2006-03-01 | — | — | EP | claimed |