Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927257 | 0.90 | NR2E1 (0.84) | NR2E1 | |
| SCHEMBL13261062 | 0.89 | NR2E1 (1.00) | NR2E1 | |
| SCHEMBL12516822 | 0.86 | NR2E1 (0.77) | NR2E1 | |
| SCHEMBL31014309 | 0.85 | NR2E1 (0.75) | NR2E1 | |
| SCHEMBL12354400 | 0.84 | NR2E1 (0.73) | NR2E1 | |
| SCHEMBL20503056 | 0.83 | NR2E1 (0.84) | NR2E1 | |
| SCHEMBL29561954 | 0.83 | NR2E1 (1.00) | NR2E1 | |
| SCHEMBL31729797 | 0.82 | NR2E1 (0.82) | NR2E1 | |
| SCHEMBL15189550 | 0.82 | NR2E1 (0.70) | NR2E1 | |
| SCHEMBL4254143 | 0.81 | NR2E1 (0.71) | NR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191449-A1 | NOVEL COMPOUNDS AS REARRANGED DURING TRANSFECTION (RET) INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016037578-A1 | NOVEL COMPOUNDS AS REARRANGED DURING TRANSFECTION (RET) INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2016-03-17 | — | — | WO | disclosed |