Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5242117 | 0.94 | DPP4 (0.42) | DPP4DPP8DPP9KDM4EALDH1A1 | |
| SCHEMBL5242329 | 0.88 | DPP4 (0.44) | DPP4DPP8DPP9 | |
| SCHEMBL5741021 | 0.86 | GCGR (0.44) | DPP4DPP8DPP9GCGR | |
| SCHEMBL5741240 | 0.83 | DPP4 (0.45) | DPP4DPP8DPP9GCGR | |
| SCHEMBL5740456 | 0.82 | DPP4 (0.45) | DPP4DPP8DPP9 | |
| SCHEMBL5239745 | 0.79 | DPP4 (0.47) | DPP4DPP8DPP9GCGR | |
| SCHEMBL5239116 | 0.78 | DPP4 (0.42) | DPP4DPP8DPP9GCGR | |
| SCHEMBL5738343 | 0.77 | KDM4E (0.42) | DPP4DPP8DPP9KDM4EALDH1A1 | |
| SCHEMBL5451844 | 0.77 | DPP4 (0.46) | DPP4DPP8DPP9 | |
| SCHEMBL5242122 | 0.77 | DPP4 (0.49) | DPP4DPP8DPP9KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678138-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Takeda Pharmaceutical Company Limited (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042488-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-12 | — | — | WO | disclosed |