Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081495 | 0.95 | SLC6A2 (0.78) | SLC6A2SLC6A4 | |
| SCHEMBL5728872 | 0.95 | SLC6A2 (0.78) | SLC6A2SLC6A4 | |
| SCHEMBL4087165 | 0.85 | SLC6A2 (0.79) | SLC6A2SLC6A4 | |
| SCHEMBL4085215 | 0.85 | SLC6A2 (0.74) | SLC6A2SLC6A4 | |
| SCHEMBL4084324 | 0.83 | SLC6A2 (1.00) | SLC6A2SLC6A4 | |
| SCHEMBL4087481 | 0.83 | SLC6A2 (1.00) | SLC6A2SLC6A4 | |
| SCHEMBL4084328 | 0.83 | SLC6A2 (1.00) | SLC6A2SLC6A4 | |
| SCHEMBL4086946 | 0.83 | SLC6A2 (0.78) | SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL4087084 | 0.82 | SLC6A2 (0.98) | SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL4087080 | 0.82 | SLC6A2 (0.98) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732887-A1 | 1-(1H-INDOL-1-YL)-3-(4-METHYLPIPERAZIN-1-YL)-1-PHENYL PROPAN-2-OL DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF THE NOREPINEPHRINE (NE) AND THE SEROTONINE (5-HT) ACTIVITY AND THE MONOAMINE REUPTAKE FOR THE TREATMENT OF VASOMOTOR SYMPTOMS (VMS) | Wyeth (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097744-A1 | 1-(1H-INDOL-1-YL)-3-(4-METHYLPIPERAZIN-1-YL)-1-PHENYL PROPAN-2-OL DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF THE NOREPINEPHRINE (NE) AND THE SEROTONINE (5-HT) ACTIVITY AND THE MONOAMINE REUPTAKE FOR THE TREATMENT OF VASOMOTOR SYMPTOMS (VMS) | WYETH (US) | 2005-10-20 | — | — | WO | disclosed |