Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.80 |
| ▸ | HTR2B | P41595 | 20/20 | 0.80 |
| ▸ | HTR2A | P28223 | 16/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3558410 | 1.00 | HTR2C (0.80) | HTR2CHTR2BHTR2A | |
| SCHEMBL13119289 | 0.90 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL3564659 | 0.87 | HTR2C (0.81) | HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL14110388 | 0.87 | HTR2C (0.81) | HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL3559810 | 0.87 | HTR2C (0.81) | HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL5741115 | 0.87 | HTR2C (0.81) | HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL3554425 | 0.87 | HTR2C (0.65) | HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL3558745 | 0.87 | HTR2C (0.87) | HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL3553213 | 0.85 | HTR2C (0.70) | HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL3556983 | 0.84 | HTR2C (0.56) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675859-A1 | MODULATORS OF SEROTONIN RECEPTORS | Bristol-Myers Squibb Company (US) | 2006-07-05 | — | — | EP | claimed |
| WO-2005035533-A1 | MODULATORS OF SEROTONIN RECEPTORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-04-21 | — | — | WO | claimed |