Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 14/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 11/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2947044 | 0.85 | BCL2L1 (0.47) | BCL2MCL1BCL2L1 | |
| SCHEMBL2944693 | 0.83 | BCL2L1 (0.59) | BCL2MCL1BCL2L1 | |
| SCHEMBL2947167 | 0.83 | BCL2L1 (0.47) | BCL2MCL1BCL2L1 | |
| SCHEMBL2951339 | 0.82 | BCL2L1 (0.57) | BCL2MCL1BCL2L1 | |
| SCHEMBL2953391 | 0.82 | BCL2L1 (0.51) | BCL2MCL1BCL2L1 | |
| SCHEMBL2946326 | 0.81 | BCL2L1 (0.47) | BCL2MCL1BCL2L1 | |
| SCHEMBL2950847 | 0.81 | BCL2L1 (0.51) | BCL2MCL1BCL2L1 | |
| SCHEMBL2948953 | 0.79 | BCL2L1 (0.50) | BCL2MCL1BCL2L1 | |
| SCHEMBL2952249 | 0.79 | BCL2L1 (0.62) | BCL2MCL1BCL2L1 | |
| SCHEMBL2945360 | 0.79 | BCL2L1 (0.51) | BCL2MCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318978-B1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LAB (US) | 2006-02-08 | — | — | EP | disclosed |