Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3972287 | 0.99 | GAA (0.53) | GAAHRH3NTRK1RETGPR119 | |
| Hydrochloric Acid SCHEMBL3971158 | 0.94 | GAA (0.55) | GAAHRH3NTRK1GPR119KMT2A | |
| Hydrochloric Acid SCHEMBL3972677 | 0.84 | KMT2A (0.45) | GAAHRH3KMT2AKDM2BPIK3CA | |
| Hydrochloric Acid SCHEMBL3973037 | 0.82 | KMT2A (0.48) | GAAHRH3GPR119KMT2AKDM2B | |
| Hydrochloric Acid SCHEMBL3973918 | 0.81 | MAPT (0.48) | GAAKMT2A | |
| Hydrochloric Acid SCHEMBL3972946 | 0.80 | MAPT (0.49) | HRH3KDM2B | |
| SCHEMBL1742633 | 0.80 | KDM4E (0.54) | GAAHRH3RETKMT2AKDM2B | |
| Hydrochloric Acid SCHEMBL3973384 | 0.79 | GAA (0.53) | GAAHRH3NTRK1KMT2AACVR1 | |
| SCHEMBL2824378 | 0.78 | GAA (0.49) | GAAHRH3GPR119KMT2AKDM2B | |
| SCHEMBL3977911 | 0.78 | HRH3 (0.47) | HRH3RETACVR1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1721896-A1 | Phenylpyridinylpiperazin derivatives, the process to make them and the compositions containing them | Les Laboratoires Servier (FR) | 2006-11-15 | — | — | EP | claimed |
| WO-2006120348-A1 | NOVEL PHENYL-PYRIDINYL-PIPERAZINE DERIVATIVES, A METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | LES LABORATOIRES SERVIER (FR) | 2006-11-16 | — | — | WO | disclosed |
| EP-1721896-A1 | Phenylpyridinylpiperazin derivatives, the process to make them and the compositions containing them | Les Laboratoires Servier (FR) | 2006-11-15 | — | — | EP | disclosed |