SCHEMBL5743734

SCHEMBL5743734

CC(C)CC1(N2CCN(C(=O)C(Cc3ccc(Cl)cc3)NC(=O)CC3NCc4ccccc43)CC2)CCS(=O)(=O)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MC4R P32245 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14279512 1.00 MC4R (1.00) MC4R
SCHEMBL14279502 0.94 MC4R (0.91) MC4R
SCHEMBL4856602 0.94 MC4R (0.91) MC4R
SCHEMBL4858824 0.94 MC4R (1.00) MC4R
SCHEMBL14279511 0.94 MC4R (1.00) MC4R
SCHEMBL14279501 0.91 MC4R (1.00) MC4R
SCHEMBL4858119 0.91 MC4R (1.00) MC4R
SCHEMBL4852772 0.91 MC4R (1.00) MC4R
SCHEMBL14279520 0.91 MC4R (1.00) MC4R
SCHEMBL14279514 0.91 MC4R (1.00) MC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469851-B1 MELANOCORTIN RECEPTOR AGONISTS LILLY CO ELI (US) 2006-10-11 EP claimed