Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 18/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700403 | 0.85 | CCR4 (0.56) | CCR4 | |
| SCHEMBL4699747 | 0.75 | CCR4 (0.57) | CCR4 | |
| SCHEMBL1969809 | 0.73 | CCR4 (0.78) | CCR4 | |
| SCHEMBL1732656 | 0.72 | CCR4 (0.77) | CCR4CCR2 | |
| SCHEMBL1731359 | 0.71 | CCR4 (1.00) | CCR4 | |
| SCHEMBL4700081 | 0.70 | CCR4 (0.57) | CCR4 | |
| SCHEMBL4701024 | 0.70 | CCR4 (0.59) | CCR4 | |
| SCHEMBL4701065 | 0.69 | CCR4 (0.61) | CCR4 | |
| SCHEMBL4700036 | 0.69 | CCR4 (0.58) | CCR4 | |
| SCHEMBL4704359 | 0.68 | CCR4 (0.56) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633729-A1 | SULPHONAMIDE COMPOUNDS THAT MODULATE CHEMOKINE RECEPTOR ACTIVITY (CCR4) | AstraZeneca AB (SE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004108692-A1 | SULPHONAMIDE COMPOUNDS THAT MODULATE CHEMOKINE RECEPTOR ACTIVITY (CCR4) | ASTRAZENECA AB (SE) | 2004-12-16 | — | — | WO | disclosed |