Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745854 | 0.91 | CALCRL (0.52) | CALCRL | |
| SCHEMBL5747041 | 0.89 | CALCRL (0.42) | CALCRL | |
| SCHEMBL4496179 | 0.89 | CALCRL (0.67) | CALCRL | |
| SCHEMBL4501992 | 0.88 | CALCRL (0.67) | CALCRL | |
| SCHEMBL4507669 | 0.82 | CALCRL (0.69) | CALCRL | |
| SCHEMBL4507754 | 0.82 | CALCRL (0.68) | CALCRL | |
| SCHEMBL4503889 | 0.81 | CALCRL (0.69) | CALCRL | |
| SCHEMBL4507890 | 0.81 | CALCRL (0.68) | CALCRL | |
| SCHEMBL2971025 | 0.81 | CALCRL (0.54) | CALCRL | |
| SCHEMBL4509548 | 0.81 | CALCRL (0.68) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689738-A2 | HETEROCYCLIC ANTI-MIGRAINE AGENTS | Bristol-Myers Squibb Company (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005056550-A2 | HETEROCYCLIC ANTI-MIGRAINE AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-23 | — | — | WO | disclosed |