Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873835 | 0.77 | HTR2A (0.32) | FFAR3 | |
| Trifluoroacetic Acid SCHEMBL18740355 | 0.76 | SLC1A2 (0.35) | CYP1A2 | |
| SCHEMBL29102688 | 0.73 | HSD17B10 (0.33) | — | |
| SCHEMBL6900137 | 0.72 | — | — | |
| SCHEMBL19730748 | 0.71 | — | — | |
| SCHEMBL18756397 | 0.71 | FFAR3 (0.30) | FFAR3 | |
| SCHEMBL1668813 | 0.71 | — | — | |
| SCHEMBL19689587 | 0.71 | KDM4E (0.34) | — | |
| Hydrochloric Acid SCHEMBL1488612 | 0.69 | — | — | |
| SCHEMBL825722 | 0.69 | KDM4E (0.38) | FFAR3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118894-A | TRPV4 receptor ligands | 犹他大学研究基金会 | 2024-12-13 | — | — | CN | disclosed |
| EP-4108675-A1 | PREPARATION AND USE OF IMMUNOSTIMULATORY COUPLING COMPLEX WHICH IS DELIVERED AND ACTIVATED IN TARGETED MANNER | Yafei Shanghai Biolog Medicine Science & Technology Co., Ltd. (CN) | 2022-12-28 | — | — | EP | disclosed |
| CN-105061350-B | The sphingosine 1-phosphate receptor modulators and Chiral Synthesis of selectivity | 赛尔基因第二国际有限公司 | 2018-05-29 | — | — | CN | disclosed |
| EP-2409704-A2 | c-Met modulators and methods of use | Exelixis Inc. (US) | 2012-01-25 | — | — | EP | disclosed |
| EP-2392565-A1 | c-Met modulators and methods of use | Exelixis Inc. (US) | 2011-12-07 | — | — | EP | disclosed |
| EP-2392564-A1 | c-Met modulators and methods of use | Exelixis Inc. (US) | 2011-12-07 | — | — | EP | disclosed |
| EP-1673085-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2011-11-09 | — | — | EP | disclosed |
| EP-2210607-B1 | N-[3-fluoro-4-({6-(methyloxy)-7-[(3-morpholin-4-ylpropyl)oxy]quinolin-4-yl}oxy)phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide for the treatment of cancer | EXELIXIS INC (US) | 2011-08-17 | — | — | EP | disclosed |
| EP-2213661-B1 | c-Met Modulators and Methods of Use | EXELIXIS INC (US) | 2011-07-20 | — | — | EP | disclosed |
| EP-2213661-A1 | c-Met Modulators and Methods of Use | Exelixis Inc. (US) | 2010-08-04 | — | — | EP | disclosed |
| US-4855452-A | N-substituted azetidine carboxylate derivatives | SHELL OIL COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4778577-A | OXIDATION OF ALCOHOL TO ACID WITH NICKEL/III/COMPOUND | SHELL OIL COMPANY (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0165636-B1 | PROCESS FOR PREPARING AZETIDINE DERIVATIVES AND INTERMEDIATES THEREIN | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-08-10 | — | — | EP | disclosed |
| EP-0165637-B1 | AZETIDINE DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-07-27 | — | — | EP | disclosed |
| US-4665197-A | NITRIC ACID OXIDATION OF 3,3-BIS/HYDROXYMETHYL/AZETIDINE/ | SHELL OIL COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| CN-86102422-A | The method for preparing azetidine derivatives | — | 1987-01-28 | — | — | CN | disclosed |
| EP-0201957-A2 | Process for the preparation of a carboxylic acid salt | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-11-20 | — | — | EP | disclosed |
| EP-0199413-A2 | Process for preparing azetidine derivatives and novel intermediates therein | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-10-29 | — | — | EP | disclosed |
| EP-0165637-A1 | Azetidine derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1985-12-27 | — | — | EP | disclosed |
| EP-0165636-A1 | Process for preparing azetidine derivatives and intermediates therein | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1985-12-27 | — | — | EP | disclosed |