Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748823 | 1.00 | KCNH2 (0.44) | KCNH2LIPGTLR8BIDMCL1 | |
| SCHEMBL5747397 | 1.00 | KCNH2 (0.44) | KCNH2LIPGTLR8BIDMCL1 | |
| SCHEMBL6115046 | 0.78 | TRPV1 (0.49) | KCNH2LIPGTLR8BIDMCL1 | |
| SCHEMBL6114788 | 0.78 | TRPV1 (0.49) | KCNH2LIPGTLR8BIDMCL1 | |
| SCHEMBL6114747 | 0.78 | TRPV1 (0.49) | KCNH2LIPGTLR8BIDMCL1 | |
| SCHEMBL6115058 | 0.78 | TRPV1 (0.49) | KCNH2LIPGTLR8BIDMCL1 | |
| SCHEMBL6114571 | 0.78 | TRPV1 (0.49) | KCNH2LIPGTLR8BIDMCL1 | |
| SCHEMBL6114475 | 0.78 | TRPV1 (0.49) | KCNH2LIPGTLR8BIDMCL1 | |
| SCHEMBL6114947 | 0.78 | TRPV1 (0.49) | KCNH2LIPGTLR8BIDMCL1 | |
| SCHEMBL5745889 | 0.77 | TLR8 (0.47) | KCNH2LIPGTLR8BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |