SCHEMBL5746385

SCHEMBL5746385

CCCCCCCCCCc1ccc2ccc3[c]ccc4ccc1c2c34

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KCNH2 Q12809 2/20 0.36
MAPT P10636 3/20 0.36
TYR P14679 2/20 0.36
CYP3A4 P08684 2/20 0.36
TP53 P04637 1/20 0.36
ALOX5 P09917 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LIPG Q9Y5X9 1/20 0.33
TLR8 Q9NR97 8/20 0.33
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5749859 1.00 MEN1 (0.38) MEN1KMT2AKCNH2MAPTTYR
SCHEMBL5747464 1.00 MEN1 (0.38) MEN1KMT2AKCNH2MAPTTYR
SCHEMBL5748032 1.00 MEN1 (0.38) MEN1KMT2AKCNH2MAPTTYR
SCHEMBL5750182 1.00 MEN1 (0.38) MEN1KMT2AKCNH2MAPTTYR
SCHEMBL5747427 1.00 MEN1 (0.38) MEN1KMT2AKCNH2MAPTTYR
SCHEMBL5748428 0.85 KCNH2 (0.38) MEN1KMT2AKCNH2MAPTCYP3A4
SCHEMBL5748904 0.85 KCNH2 (0.38) MEN1KMT2AKCNH2MAPTCYP3A4
SCHEMBL5748721 0.85 KCNH2 (0.38) MEN1KMT2AKCNH2MAPTCYP3A4
SCHEMBL2817093 0.84 MEN1 (0.49) MEN1KMT2AKCNH2MAPTTYR
SCHEMBL2811654 0.84 MEN1 (0.49) MEN1KMT2AKCNH2MAPTTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed