Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.33 |
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770307 | 0.90 | KCNH2 (0.36) | KCNH2PDE2APDE10AEGFRPDE7A | |
| SCHEMBL29692824 | 0.90 | KCNH2 (0.36) | KCNH2PDE2APDE10AEGFRPDE7A | |
| SCHEMBL592329 | 0.86 | EGFR (0.38) | KCNH2EGFR | |
| SCHEMBL29692873 | 0.86 | EGFR (0.38) | KCNH2EGFR | |
| SCHEMBL3618668 | 0.79 | CSF1R (0.35) | KCNH2PTPN11 | |
| SCHEMBL25492677 | 0.77 | MAPT (0.37) | — | |
| SCHEMBL3824367 | 0.77 | KDM4E (0.39) | EGFR | |
| SCHEMBL29692936 | 0.77 | PDE2A (0.39) | KCNH2PDE2APDE10AEGFR | |
| SCHEMBL590921 | 0.77 | PDE2A (0.39) | KCNH2PDE2APDE10AEGFR | |
| SCHEMBL14161282 | 0.76 | EGFR (0.36) | KCNH2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578743-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-29 | — | — | EP | disclosed |
| EP-1578743-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004058144-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-07-15 | — | — | WO | disclosed |