⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129884 | 0.50 | — | — | |
| SCHEMBL2353104 | 0.47 | — | — | |
| SCHEMBL27797375 | 0.33 | — | — | |
| SCHEMBL27750356 | 0.33 | — | — | |
| SCHEMBL9442113 | 0.33 | — | — | |
| Methane SCHEMBL23044967 | 0.33 | — | — | |
| SCHEMBL28187572 | 0.33 | — | — | |
| SCHEMBL21933188 | 0.33 | — | — | |
| Charcoal, Activated SCHEMBL10526137 | 0.33 | — | — | |
| SCHEMBL10365277 | 0.33 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615885-A1 | B -FUSED BICYCLIC PROLINE DERIVATIVES AND THEIR USE FOR TREATING ARTHRITIC CONDITIONS | Warner-Lambert Company LLC (US) | 2006-01-18 | — | — | EP | disclosed |
| EP-1615886-A1 | [C]-FUSED BICYCLIC PROLINE DERIVATIVES AND THEIR USE FOR TREATING ARTHRITIC CONDITIONS | Warner-Lambert Company LLC (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20050143427-A1 | [B]-fused bicyclic proline derivatives and their use for treating arthritic conditions | BARVIAN NICOLE C (US) | 2005-06-30 | — | — | US | disclosed |
| US-20050137215-A1 | [C]-fused bicyclic proline derivatives and their use for treating arthritic conditions | GUZZO PETER R (US) | 2005-06-23 | — | — | US | disclosed |
| WO-2004092132-A1 | [B]-FUSED BICYCLIC PROLINE DERIVATIVES AND THEIR USE FOR TREATING ARTHRITIC CONDITIONS | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-28 | — | — | WO | disclosed |
| WO-2004092134-A1 | [C]-FUSED BICYCLIC PROLINE DERIVATIVES AND THEIR USE FOR TREATING ARTHRITIC CONDITIONS | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-28 | — | — | WO | disclosed |