SCHEMBL5747599

SCHEMBL5747599

COCCc1nc2c(N)nc3ccccc3c2n1CCCCCC(N)=O

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.60
TLR8 Q9NR97 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5616967 0.89 TLR7 (0.67) TLR7TLR8
SCHEMBL20806194 0.89 TLR7 (0.61) TLR7TLR8
SCHEMBL3862244 0.88 TLR7 (0.75) TLR7TLR8
SCHEMBL5616933 0.88 TLR7 (0.69) TLR7TLR8
SCHEMBL1950333 0.87 TLR7 (0.62) TLR7TLR8
SCHEMBL28418118 0.87 TLR7 (0.60) TLR7
SCHEMBL5616930 0.87 TLR7 (0.77) TLR7TLR8
SCHEMBL3865268 0.87 TLR7 (0.66) TLR7TLR8
SCHEMBL13937536 0.87 TLR7 (0.60) TLR7TLR8
SCHEMBL1951894 0.87 TLR7 (0.77) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1187613-B9 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2006-10-25 EP claimed
EP-1187613-B1 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2006-08-09 EP claimed
US-6451810-B1 AID IN CYTOKINE BIOSYNTHESIS 3M INNOVATIVE PROPERTIES COMPANY 2002-09-17 US claimed