Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 15/20 | 0.68 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747970 | 1.00 | KCNH2 (0.68) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL5743547 | 1.00 | KCNH2 (0.68) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL5743550 | 1.00 | KCNH2 (0.68) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL5747965 | 1.00 | KCNH2 (0.68) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL5747717 | 0.99 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL6079059 | 0.99 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL6079057 | 0.99 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL5747723 | 0.99 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL5747720 | 0.99 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL6078752 | 0.92 | KCNH2 (0.81) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578743-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-29 | — | — | EP | disclosed |
| EP-1578743-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004058144-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-07-15 | — | — | WO | disclosed |