SCHEMBL5748091

SCHEMBL5748091

N#CCC(O)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27311602 1.00
SCHEMBL5748082 1.00
Hydrochloric Acid SCHEMBL30792521 0.97
SCHEMBL196713 0.81
SCHEMBL4970022 0.75 GABRR1 (0.39)
SCHEMBL1956609 0.73
SCHEMBL7558453 0.73
SCHEMBL7560829 0.73
SCHEMBL11797163 0.73
SCHEMBL9491337 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1180095-B1 4-CYANO-3-HYDROXY BUTANOYL HYDRAZINES, DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF UNIV MICHIGAN STATE (US) 2006-08-30 EP claimed
US-6114566-A 4-cyano-3-hydroxybutanoyl hydrazines, derivatives and process for the preparation thereof BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 2000-09-05 US claimed
EP-0269258-A2 Process for the preparation of a pyrrolidinol compound A.H. ROBINS COMPANY, INCORPORATED (US) 1988-06-01 EP claimed
WO-2024137674-A2 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-06-27 WO disclosed
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 WO disclosed
US-8334132-B2 Process for production of a betaine such as carnitine MITSUBISHI RAYON CO., LTD. (JP) 2012-12-18 US disclosed
US-7714166-B2 Process for producing carnitinamide MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-05-11 US disclosed
US-20090325246-A1 PROCESS FOR PRODUCTION OF BETAINE MITSUBISHI RAYON CO., LTD. (JP) 2009-12-31 US disclosed
US-20090143616-A1 Process for Producing Carnitinamide MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-06-04 US disclosed
EP-1180095-B1 4-CYANO-3-HYDROXY BUTANOYL HYDRAZINES, DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF UNIV MICHIGAN STATE (US) 2006-08-30 EP disclosed
EP-1180095-A4 4-CYANO-3-HYDROXY BUTANOYL HYDRAZINES, DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF UNIV MICHIGAN STATE (US) 2005-01-26 EP disclosed
EP-1180095-A1 4-CYANO-3-HYDROXY BUTANOYL HYDRAZINES, DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF MICHIGAN STATE UNIVERSITY (US) 2002-02-20 EP disclosed
WO-2000071503-A1 4-CYANO-3-HYDROXY BUTANOYL HYDRAZINES, DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF MICHIGAN STATE UNIVERSITY (US) 2000-11-30 WO disclosed
US-6114566-A 4-cyano-3-hydroxybutanoyl hydrazines, derivatives and process for the preparation thereof BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 2000-09-05 US disclosed
US-4990683-A Process for preparing 3-pyrrolidinols A. H. ROBINS COMPANY, INCORPORATED (US) 1991-02-05 US disclosed
US-4990683-A Process for preparing 3-pyrrolidinols A. H. ROBINS COMPANY, INCORPORATED (US) 1991-02-05 US disclosed
EP-0269258-A2 Process for the preparation of a pyrrolidinol compound A.H. ROBINS COMPANY, INCORPORATED (US) 1988-06-01 EP disclosed