Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750027 | 0.89 | KCNH2 (0.48) | KCNH2CNR1CNR2SLC2A1 | |
| SCHEMBL5749905 | 0.84 | KCNH2 (0.49) | KCNH2CNR1CNR2SLC2A1 | |
| SCHEMBL5749909 | 0.84 | KCNH2 (0.57) | KCNH2CNR1CNR2 | |
| SCHEMBL5750585 | 0.83 | KCNH2 (0.49) | KCNH2CNR1CNR2SLC2A1 | |
| SCHEMBL5750070 | 0.81 | KCNH2 (0.47) | KCNH2CNR1CNR2 | |
| SCHEMBL5750363 | 0.80 | KCNH2 (0.46) | KCNH2CNR1CNR2SLC2A1 | |
| SCHEMBL5749942 | 0.79 | KCNH2 (0.45) | KCNH2CNR1CNR2 | |
| SCHEMBL5746005 | 0.76 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL5751526 | 0.74 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL14341308 | 0.72 | KCNH2 (0.51) | KCNH2CNR1CNR2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419155-B1 | PIPERIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2006-11-08 | — | — | EP | disclosed |