Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749723 | 0.91 | TLR7 (0.45) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL5750269 | 0.86 | TLR7 (0.43) | TLR7TLR8ALDH1A1LMNAPOLB | |
| SCHEMBL5749137 | 0.84 | TLR7 (0.49) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL5749982 | 0.84 | TLR7 (0.51) | TLR7TLR8BACE1LMNAPOLB | |
| SCHEMBL5746792 | 0.83 | TLR7 (0.51) | TLR7TLR8ALDH1A1LMNAPOLB | |
| SCHEMBL5748536 | 0.82 | TLR7 (0.42) | TLR7NPC1RAB9AALDH1A1F2 | |
| SCHEMBL5747394 | 0.82 | TLR7 (0.56) | TLR7TLR8ALDH1A1LMNAPOLB | |
| SCHEMBL5749071 | 0.81 | TLR7 (0.48) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL5749508 | 0.81 | TLR7 (0.49) | TLR7TLR8ALDH1A1LMNAPOLB | |
| SCHEMBL5747317 | 0.80 | TLR7 (0.47) | TLR7TLR8ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187613-B9 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2006-10-25 | — | — | EP | claimed |
| EP-1187613-B1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2006-08-09 | — | — | EP | claimed |
| US-6451810-B1 | AID IN CYTOKINE BIOSYNTHESIS | 3M INNOVATIVE PROPERTIES COMPANY | 2002-09-17 | — | — | US | claimed |