Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14953136 | 1.00 | NPC1 (0.46) | NPC1RAB9ALMNAPTGS2POLB | |
| SCHEMBL30485790 | 1.00 | NPC1 (0.46) | NPC1RAB9ALMNAPTGS2POLB | |
| SCHEMBL14032738 | 0.99 | NPC1 (0.47) | NPC1RAB9ALMNAPTGS2POLB | |
| SCHEMBL28127188 | 0.95 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL11088731 | 0.87 | NPC1 (0.43) | NPC1RAB9ALMNAPTGS2POLB | |
| SCHEMBL30573270 | 0.87 | NPC1 (0.43) | NPC1RAB9ALMNAPTGS2POLB | |
| SCHEMBL26657999 | 0.87 | NPC1 (0.43) | NPC1RAB9ALMNAPTGS2POLB | |
| SCHEMBL7577937 | 0.87 | NPC1 (0.43) | NPC1RAB9ALMNAPTGS2POLB | |
| SCHEMBL30968393 | 0.87 | NPC1 (0.43) | NPC1RAB9ALMNAPTGS2POLB | |
| SCHEMBL26658077 | 0.87 | NPC1 (0.43) | NPC1RAB9ALMNAPTGS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803368-B | Color-stable, halogen-free flame retardant compositions | DOW GLOBAL TECHNOLOGIES INC | 2014-03-12 | — | — | CN | disclosed |
| EP-2601257-A1 | STABILIZED PHOTOACTIVE COMPOSITION AND USE THEREOF | ENI S.p.A. (IT) | 2013-06-12 | — | — | EP | disclosed |
| CN-103080203-A | Stabilized photoactive composition and use thereof | ENI SPA | 2013-05-01 | — | — | CN | disclosed |
| CN-102803368-A | Color-stable, Halogen-free Flame Retardant Compositions | DOW GLOBAL TECHNOLOGIES INC | 2012-11-28 | — | — | CN | disclosed |
| CN-101198652-B | Polycarbonate resin composition and molded article | MITSUBISHI ENG PLASTICS CORP | 2012-07-04 | — | — | CN | disclosed |
| WO-2012017046-A1 | STABILIZED PHOTOACTIVE COMPOSITION AND USE THEREOF | ENI S.P.A. (IT) | 2012-02-09 | — | — | WO | disclosed |
| CN-101198652-A | Polycarbonate resin composition and molded article | MITSUBISHI ENG PLASTICS CORP (JP) | 2008-06-11 | — | — | CN | disclosed |
| EP-0821709-A1 | POLYKETONE POLYMER COMPOSITION | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033236-A1 | POLYKETONE POLYMER COMPOSITION | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1996-10-24 | — | — | WO | disclosed |