Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 17/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.48 |
| ▸ | PDE4A | P27815 | 11/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746211 | 0.91 | PDE4D (0.56) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5750307 | 0.88 | PDE4D (0.65) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5747561 | 0.85 | PDE4D (0.65) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4028550 | 0.83 | PDE4D (0.73) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4026556 | 0.82 | PDE4D (0.73) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4030622 | 0.82 | PDE4D (0.80) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5748805 | 0.81 | PDE4D (0.60) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL4029693 | 0.81 | PDE4D (0.79) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5745696 | 0.80 | PDE4D (0.59) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL4035094 | 0.80 | PDE4D (0.85) | PDE4DPDE4BPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620429-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Glenmark Pharmaceuticals S.A. (CH) | 2006-02-01 | — | — | EP | claimed |
| WO-2004089940-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS S.A. (US) | 2004-10-21 | — | — | WO | claimed |