Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.46 |
| ▸ | LPL | P06858 | 2/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747932 | 1.00 | PARP1 (0.49) | PARP1S1PR1S1PR3SKP2HTR2A | |
| SCHEMBL5747036 | 1.00 | PARP1 (0.49) | PARP1S1PR1S1PR3SKP2HTR2A | |
| SCHEMBL5745316 | 0.88 | PARP1 (0.45) | PARP1S1PR1S1PR3SKP2HTR2A | |
| SCHEMBL5747795 | 0.88 | PARP1 (0.45) | PARP1S1PR1S1PR3SKP2HTR2A | |
| SCHEMBL5747218 | 0.88 | PARP1 (0.45) | PARP1S1PR1S1PR3SKP2HTR2A | |
| SCHEMBL5745548 | 0.88 | PARP1 (0.45) | PARP1S1PR1S1PR3SKP2HTR2A | |
| SCHEMBL5748855 | 0.88 | PARP1 (0.45) | PARP1S1PR1S1PR3SKP2HTR2A | |
| SCHEMBL5751333 | 0.88 | PARP1 (0.45) | PARP1S1PR1S1PR3SKP2HTR2A | |
| SCHEMBL5747458 | 0.88 | PARP1 (0.49) | PARP1SKP2HTR2ATLR8LPL | |
| SCHEMBL5749294 | 0.88 | PARP1 (0.49) | PARP1SKP2HTR2ATLR8LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |